Gene information
Official symbol THPO
Official full name thrombopoietin
Gene type protein-coding gene
Chromosome3q27.1
Alias symbolTPO; MPLLG
Previous symbolMGDF
Gene familyReceptor ligands
Resources
Entrez Gene 7066
HGNC HGNC:11795
Ensembl ENSG00000090534
Vega OTTHUMG00000156745
UCSC uc003fol.2
GO terms: 21 records
GO Description Category LogP Number of genes Detail
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0008283 cell population proliferation GO Biological Processes -17.2298624 68 More
GO:0030097 hemopoiesis GO Biological Processes -14.1443585 71 More
GO:0030099 myeloid cell differentiation GO Biological Processes -6.71806250 15 More
GO:0030219 megakaryocyte differentiation GO Biological Processes -3.12309097 6 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051897 positive regulation of protein kinase B signaling GO Biological Processes -23.7578366 39 More
GO:0060348 bone development GO Biological Processes -12.2474877 36 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0070374 positive regulation of ERK1 and ERK2 cascade GO Biological Processes -34.9831828 64 More
GO:0071216 cellular response to biotic stimulus GO Biological Processes -28.1549742 59 More
GO:0071219 cellular response to molecule of bacterial origin GO Biological Processes -28.3848077 56 More
GO:0071222 cellular response to lipopolysaccharide GO Biological Processes -26.0381191 52 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0072091 regulation of stem cell proliferation GO Biological Processes -6.89052200 13 More
Drug-Gene interaction
view
Related drugs: 75 records
Drug name Interaction type Source PMID View
(r,s)-indatraline DTC view
(s)apomorphine DTC view
amoxapine DTC view
azacitidine DTC view
benzamil DTC view
busulfan NCI 7742532 view
camptothecin DTC view
chelerythrine DTC view
chembl1169388 DTC view
chembl1256364 DTC view
chembl24983 DTC view
chembl291143 DTC view
chembl297784 DTC view
chembl323356 DTC view
chembl35482 DTC view
chembl375270 DTC view
chembl429095 DTC view
chembl445102 DTC view
chlorpromazine DTC view
clemastine DTC view
clotrimazole DTC view
desipramine DTC view
dihydrexidine DTC view
dilazep DTC view
diphenyleneiodonium DTC view
disulfiram DTC view
elliptecine DTC view
emodin DTC view
fenretinide DTC view
fluspirilene DTC view
furoxan DTC view
genistein DTC view
gr-127935 DTC view
hydralazine DTC view
hydroquinone DTC view
imetit DTC view
iodoacetamide DTC view
kenpaullone DTC view
l-765314 DTC view
lapachone DTC view
metergoline DTC view
mibefradil DTC view
mitoxantrone DTC view
myricetin DTC view
n-ethylmaleimide DTC view
niclosamide DTC view
nordihydroguaiaretic acid DTC view
papaverine DTC view
paroxetine hydrochloride DTC view
pd-169316 DTC view
perphenazine DTC view
phenamil methanesulfonate DTC view
pimozide DTC view
protriptyline DTC view
pseudoephedrine DTC view
pyrrolidine dithiocarbamate DTC view
raloxifene DTC view
reserpine DTC view
rutaecarpine DTC view
s-methyl-d-thiocitrulline DTC view
salmeterol xinafoate DTC view
sanguinarium DTC view
sb-224289 DTC view
sobuzoxane DTC view
spermidine DTC view
su-9516 DTC view
tamoxifen citrate DTC view
terfenadine DTC view
tpck DTC view
trifluoperazine DTC view
tyrphostin a9 DTC view
tyrphostin ag 879 DTC view
urea NCI 9726418 view
vanoxerine DTC view
win-552122 DTC view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_000460.4:c.5713A>G genomics myocardial infarction[diagnosis] myocardial infarction Webb KE et al. Atherosclerosis. 2001
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